The first lady's trip is "fantastic and really encouraging", said Tom Hart, executive director for North America at the ONE Campaign, an advocacy group dedicated to combating global poverty and disease in Africa and elsewhere.
Mrs Trump has been touring Africa and made her first stop in Ghana on 2 October 2018.
Trump also had tea with Ghana's first lady, Rebecca Akufo-Addo, at the presidential palace. She approached a crowd of children in royal-blue-and-orange school uniforms who sang in English, "Welcome, welcome, welcome, welcome all of you". If her goal in Africa was to mend relationships - which may have been suffering following the President's alleged "shithole countries" comment earlier this summer - she seems to have missed the mark completely.
The criticism was not universal.
Mrs. Trump arrived at The Nest orphanage on Friday after helping feed baby elephants, still clad in the riding trousers and tall brown boots she had worn on a safari.
"She loves meeting people, learning new things, and being around kids", Grisham said.
"There are so many countries in Africa, but she chose to come here", the queen mother said. "It's exhausted and it's old and it's inaccurate".
However, in contrast to visits by former US President Barack Obama and his wife Michelle, her tour has not attracted large crowds or much fervour.
Back at the orphanage, Mrs. Trump left the same way she arrived.
After the talks, Melania is scheduled to watch a performance by Sarakasi dancers at the Kenya National Theater. She delighted in holding babies and held hands with older children, who sang and danced.
Melania spent much of her time expressing her thanks to her hosts for welcoming her.
United States First Lady Melania Trump took it in her stride when she was almost upended by a baby elephant she was feeding in Kenya. She administered them formula in oversized baby bottles, patted the animals on their heads and inspected their floppy ears. She emerged without a smudge.
A secret service agent accompanying her was quick to hold her to safety, although the baby elephant calmly went on with its business while Melania regained her footing with a smile. Throughout her trip, observers have been trying to read the reasons behind her journey, searching for clues that might place her in studied opposition to her husband's harshly leveled stereotypes about African nations. She did not appear to be injured.
She also saw a site where 105 tons of ivory was burned as part of an effort to discourage the trade.
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