Can Chloroquine Prevent or Cure COVID-19?

Tuesday, 24 Mar, 2020

"An array of drugs approved for other indications as well as several investigational drugs are being studied in several hundred clinical trials that are underway across the globe", the CDC webpage states. "Now, this is a common malaria drug", Trump said during a briefing last Thursday. In a smaller sub-group of patients in this study who received an additional antibiotic, azithromycin (commonly available as Zithromax in the United States) together with hydroxychloroquine, 100 percent of patients had no virus detected at day six.

Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases (NIAID), said on Friday that there's no definitive proof that chloroquine, an anti-malaria drug, works against the CCP virus.

Bloomsberg reported that two people were hospitalised in Lagos, Nigeria, after the demand for the drug surged during the current, new coronavirus outbreak. "I feel very confident", he said.

They used the drug combination, meant to treat malaria, arthritis, and various other ailments, on 26 coronavirus patients. They did not discuss treatment side effects.

The Nigeria Center for Disease Control (NCDC) cautioned citizens from self-medicating with chloroquine. The team eventually identified 24 drugs approved by the Food and Drug Administration to treat such seemingly unrelated diseases as cancer, Parkinson's disease and hypertension. The World Health Organization's large worldwide SOLIDARITY trial will look at these two drugs along with Kaletra (alone or in combination with interferon-beta) and Gilead Sciences' experimental antiviral remdesivir. It further added that high-risk contacts of a positive case who are taking the medicine should remain in home quarantine while on the drug.

The WHO has already launched a global mega trial of four most promising treatments for coronavirus, including the combination of hydroxychloroquine and choloroquine.

To come up with the list, hundreds of researchers embarked on an unusual study of the genes of the coronavirus, also called SARS-CoV-2.

In other words, the drug is not approved broadly, as Trump initially said, but will be given to patients only after a doctor requests it, and primarily for the objective of studying its effects and before data is available to certify that it works and is safe.

Because of a shortage of chloroquine in China, and the toxicity of chloroquine that can be fatal if overused, Wang's team also tested hydroxychloroquine in primates and found that it had the same effect, according to a report published in Cell Discovery. So I was talking a purely medical, scientific standpoint, and the president was trying to bring hope to the people. There have already been reports of serious toxicity in people using chloroquine for prevention without medical supervision. Hopefully, they will BOTH (H works better with A, International Journal of Antimicrobial Agents).

Dr. Michel Yao, Africa emergency response program manager for the World Health Organization, told CNN there are 20 drugs and the same number of vaccines under clinical trial, and it is too early to make recommendations about the efficacy of any for the treatment of the virus.